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                                                                                                                                                                                                                                                                                                                                                                                                         clinical chemistry & research solutions
                                                                                                                                                                                                                                                             3. Generation Total Antioxidant Status                              Total Oxidant Status




 ®


                                                                                                                                                                                                                                                                                                                                 a sample is measured, and this is called total antioxidant capacity
                                                                                                                                                                                                                                                                        Reactive oxygen and nitrogen species are produced in metabolic
                                   Research & Clinical Chemistry Assay Kits                                                                                                                                                                                             and  physiological  processes,  measurement  of  the  combined   (TAC),  total  antioxidant  activity  (TAA),  total  antioxidant  power


                                                                                                                                                                                                                                                                        nonenzymatic antioxidant capacity of biological fluids and other   (TAOP),  total  antioxidant  status  (TAS),  total  antioxidant
                                                                                                                                                                                                                                                                        samples  provides  an  indication  of  the  overall  capability  to   response(TAR), or other synonyms.

                                                                                                                                                                                                                                                                        counteract  reactive  oxygen  species  (ROS).  Under  certain



                                                                                                                                                                                                                                                                        conditions, the increase in oxidants and decrease in antioxidants   Serum (or plasma) concentrations of different oxidant species can
                            Paraoxonase Assay Kit                      Native Thiol Status Assay Kit                                                                                                                                                                    cannot be prevented, and the oxidative stress or   in over 100   be measured in laboratories separately, but the measurements are

                                    PON1                                          -SH                   NEW                                                                                                                                                             disorders, develops                                      time-consuming,  labor-intensive  and  costly  and  require
                                                                                                                                                                                                                                                                                                                                 complicated  techniques.  Since  the  measurement  of  different
                                                                                                                                                                                                                                                                        Antioxidant molecules prevent or inhibit these harmful reactions   oxidant molecules separately is not practical and their   oxidant
                             Arylesterase Assay Kit                     Dynamic Disulfide Status                                                                                                                                                                        Serum (or plasma) concentrations of different antioxidants can be   effects are additive, the total oxidant status (TOS) of a sample is


                                    ARES                                         -S-S                   NEW                                                                                                                                                             measured in laboratories separately, but the measurements are   measured and this is named total peroxide (TP), serum oxidation
                                                                                                                                                                                                                                                                        time-consuming, labor-intensive, costly, and require complicated   activity (SOA), reactive oxygen metabolites (ROM) or some other

                                                                                                                                                                                                                                                                        techniques. Because the measurement measurement of different   synonyms.
                                                                        Total Thiol Status Assay Kit                                                                                                                                                                    antioxidant  molecules  separately  is  not  practical  and  their
                          Ischemia Modified Albumin                               -SH                   NEW                                                                                                                                                             antioxidant effects are not additive, the total antioxidant capacity of                                                                                                                                          Princible of the Assay


                                    IMA                                                                                                                                                                             • First and unique kit which reagents, calibrators and QC                                                                                                                                                                                                            Zinc found in the samples change th






                                                                                                                                                                                                                      materials are liquid and stable.                  Components                                                                                                     Components                                                                                        548 nm is proportional to total zin

                                                                             Zinc Assay Kit                                                                                                                                                                             R1 (Buffer)                        1 x  30 ml                                                                  R1 (Buffer)                       1 x  30 ml
                                                                                  Zn                    NEW                                                                                                         • Ready to use                                      R2 (ABTS Radical Cation)           1 x  8 ml                                                                   R2 (ABTS Radical Cation)          1 x  8 ml




                        Total Antioxidant Status Assay Kit                                                                                                                                                          • Colorimetric (660 nm)                             Standard                           1 x  4   ml           TOS Test Principle                                    Standard                          1 x  4   ml


                                    TAS                                     Copper Assay Kit                                                                                                                        • Total Antioxidant Status Direct Measurement Kit   QC Level 1                         1 x  4   ml           Oxidants  present  in  the  sample  oxidize  the  ferrous  ion–chelator   QC Level 1    1 x  4   ml
                                                                                  Cu                    NEW                                                                                                                                                             QC Level 2                         1 x  4   ml                                                                 QC Level 2                        1 x  4   ml
                                                                                                                                                                                                                    • Fully automated and manually measurement options                                                           complex to ferric ion. The oxidation reaction is prolonged by enhancer
                         Total Oxidant Status Assay Kit                                                                                                                                                             • Long lifetimes of the reagents, calibrators and QC materials                                               molecules, which are abundantly present in the reaction medium. The                                                                                           Sensitive and accurate


                                    TOS                                                                                                                                                                             • Suitable for serum, plasma, body fluids and tissue samples                                                 ferric ion makes a colored complex with chromogen in an acidic                                                                                                Fast and convenient
                                                                                                                                                                                                                                                                                                                                 medium.  The  color  intensity,  which  can  be  measured

                                                                         Phosphorus (Inorganic)                                                                                                                                                                        TAS Test Principle                                        spectrophotometrically,  is  related  to  the  total  amount  of  oxidant   • First and unique kit which reagents and
                            Oxidative Stress Index                                P                     NEW                                                                                                         • Suitable for plants, nutrients and oil extracts                                                            molecules  present  in  the  sample.  The  assay  is  calibrated  with     calibrators are liquid and stable.                                                 High reagent stability and ve

                                    OSI                                                                                                                                                                             • High analytical performance charecteristics      Antioxidants in the sample reduce dark blue-green colored ABTS   hydrogen  peroxide  and  the  results  are  expressed  in  terms  of   • Ready to use                                                                  Low interference in biologica

                                                                                                                                                                                                                                                                       radical to colorless reduced ABTS form. The change of absorbance
                                                                                                                                                                                                                                                                                                                                 micromolar  hydrogen  peroxide  equivalent  per  liter  (µmol
                                                                 Nadp-Dependent Isocitrate Dehyrogenase                                                                                                             • High precision                                   at 660 nm is related with total antioxidant level of the sample. The   H2O2Equiv./L)                                                                                                                                    Easy to apply simple procedur
                                                                              NADP-IDH                  NEW                                                                                                         • High linearity                                   assay is calibrated with a stable antioxidant standard solution which                                            • Colorimetric (530 nm)

 ISO  ISO  ISO  OHSAS                                                                                                                                                                                                                                                  is traditionally named as Trolox Equivalent that is a vitamin E analog .                                                                                                                                                Automated, colorimetric (548n
 9001  14001  13485  18001                                                                                                                                                                                          • High sensitivity                                                                                                                                                  • Total Oxidant Status Direct Measurement Kit                                                          Measuring in variety of sampl







            Oksidatif Stres Testleri Yayın Sayısında
                                                                                                                                                                                                                                                                                                                                                                                        • Fully automated and manually measurement options











                                                                                  NO







                                                                                                                                                                                                                                                                                                                                                                                        • Suitable for serum, heparinized plasma, body

 C O N T A C T                                                                Nitric Oxide              UD                                                                                                          Generation Comparison Table                                                                 Oxidative Stress Index (OSI)                                            • Long lifetimes of the reagents and calibrators




 Mücahitler Mahallesi 52012 Nolu Cadde                                                                                                                                                                                                                                    Rel Assay TAS                                                                                                   fluids and tissue samples
                                                                                                                                                                                                                                                                                  ®
 No:10/1 Şehitkamil/Gaziantep/Türkiye                                                                                                                                                                                                          1. Generation  2. Generation  3. Generation                     TAS                 TOS                                                  • High analytical performance charecteristics                                                      [Precision]
 Phone: +90 342. 230 37 52                                                                                                                                                                                            Reagents                 Lyophilized  Liquid        Liquid
 Fax: +90 342. 220 49 87                                                                                                                                                                                              Reagent Life             Short        Medium        Long (1 Year)                                                                                                 • High precision                                                                                   Intra-assay was determined on 30
 e-mail: relassay@relassay.com  Dünya Lideriyiz                                                               ®                                                                                                       Calibrators              Lyophilized  Lyophilized   Liquid                                                                                                        • High linearity                                                                                   controls. The %CV results were 2.



                                                                                                                                                                                                                                               Short
                                                                                                                                                                                                                      Calibrator Life
                                                                                                                                                                                                                                                            Short
                                                                                                                                                                                                                                                                          Long (1 Year)


                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           results were 3.54.

                                                                                                                                                                                                                                                                                                                                                                                        • High sensitivity



                                                                                                                                                                                                                                                                          Liquid
                                                                                                                                                                                                                      QC Materials


                                                                                                                                                                                                                                                            Lyophilized

                                                                                                                                                                                                                                               Lyophilized





                                                                                                                                                                                                                                                                          Long (1 Year)
                                                                                                                                                                                                                                                            Short
                                                                                                                                                                                                                      QC Material Life
                                                                                                                                                                                                                                               Short












                                                                                                                                                                                                                                                                                                                         OSI
                                                                                                                                                                                                                                                            OK
                                                                                                                                                                                                                                               Interference
                                                                                                                                                                                                                                                                          OK
                                                                                                                                                                                                                      Tissue working






                                                                                                                                                                                                                      Linearity
                                                                                                                                                                                                                                                            High
                                                                                                                                                                                                                                                                          High
                                                                                                                                                                                                                                               Low


                                                                                                                                                                                                                                                                                                              OSI is a new indicator for oxidative stress.                              • Available of lipoprotein  oxidation reaction curve



                                                                                                                                                                                                                                                                                                       To determine  OSI, TAS and TOS levels measured and the results
                                                                                                                                                                                                                                                                                                                  placed in the following table.

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